Evidence supporting the use of: Vitamin E (alpha-tocopherol acetate)
For the health condition: Free Radical Damage

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, particularly in the form of alpha-tocopherol acetate, is scientifically recognized for its role as an antioxidant, meaning it helps to neutralize free radicals—unstable molecules that can damage cells and contribute to oxidative stress and tissue injury. Numerous laboratory and animal studies demonstrate that Vitamin E can reduce lipid peroxidation and protect cell membranes from oxidative damage. Human studies have also shown that Vitamin E levels tend to decrease in situations of increased oxidative stress, and supplementation can raise antioxidant status in the body.

However, while there is strong biochemical rationale and laboratory evidence for Vitamin E’s antioxidant effects, clinical evidence supporting its use to prevent or treat diseases specifically caused by free radical damage in humans is mixed. Some observational studies link higher Vitamin E intake to lower rates of chronic diseases thought to involve oxidative stress, such as cardiovascular disease and certain neurodegenerative conditions. However, large randomized controlled trials (RCTs) with Vitamin E supplementation have not consistently shown significant benefit in reducing the incidence or progression of these diseases, and in some cases, high-dose supplementation has been associated with increased risk.

In summary, the use of Vitamin E to support or treat free radical damage is grounded in solid scientific understanding of its antioxidant properties, but high-quality clinical evidence for therapeutic benefit in disease prevention or treatment is inconclusive.

More about Vitamin E (alpha-tocopherol acetate)
More about Free Radical Damage

Other ingredients used for Free Radical Damage

7-hydroxymatairesinol (HMR)
acai berry
acetyl l-carnitine
alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
l-carnosine
l-cysteine
l-glutathione
l-glycine
lentinula edodes mycelia
lutein
matcha
melatonin
mixed carotenoids
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic acids
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
whey protein
zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
Amethoflavone
Ankaflavin
Apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
Antirrhinin
Avocado
Amentoflavone
Acacetin
Allophycocyanin
Alpha-Lipoic Acid
Ascorbigen
Astragaloside
anthocyanidins
Algal protein
Acer Truncatum bunge
anthocyanosides
Argan nut oil
Apocarotenal
Apocynin
Arctiin
Arjunolic acid
Beta-hydroxybutyrate
beta-zeacarotene
Brassica
Bok Choy
Baccosides
BHT (Butylated Hydroxytoluene)
Benfotiamine
Basidiomycota
Betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
Bioflavonoids
bacoside
Baicalin
Caffeic Acid
Camellia sinensis
Carnosine
Chebulic acid
Cashew
Cichoric acid
Chocolate
Capsorubin
Carnosol
Cupric ascorbate
C-Phycocyanin
Carotene (unspecified)
Chebulinic acid
Crocetin
Canthaxanthin
Crypthecodinium
Capsanthin
Carnosic acid
Dunaliella salina
Dismutase
Delphinidin
Dunaliella
Dehydroascorbic acid
Dumontiaceae
Desoxyrhaponticin
Dragon Fruit
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Diosmetin
epicatechin
Ellagic Acid
Ergothioneine
Emblicanin
Erythorbic acid
Ethylgallate
Eriodictyol
Ecklonia
Fucoidan
Flavin mononucleotide
Fatty acids
Furanosterols
Flavanones
Flavoglycosides
Flavans
Flavonones
Flavones
Ginsenosides
Glucan peptides
Gac
Gamma-Glutamylcysteine
Garcinone C
Garcinone E
Glutathione
Gamma-carotene
walnut

Products containing Vitamin E (alpha-tocopherol acetate)

We currently have no products on Caring Sunshine that contain this ingredient.