Evidence supporting the use of: Vitamin B9 (methyltetrahydrofolate)
For the body system: Female Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin B9, particularly in its active form as methyltetrahydrofolate (5-MTHF), is strongly supported by scientific evidence for its role in supporting the female reproductive system. Folate is essential for DNA synthesis, cell division, and tissue growth, all of which are crucial during periods of rapid cell turnover such as pregnancy. Adequate folate status before and during early pregnancy is well-established to significantly reduce the risk of neural tube defects (NTDs) in the developing fetus, a fact recognized by numerous health authorities, including the CDC, WHO, and ACOG. Women of childbearing age are universally advised to ensure sufficient intake of folate—either through diet, supplementation, or both. Methyltetrahydrofolate, the bioactive form, is particularly recommended for women with certain genetic polymorphisms (e.g., MTHFR mutations) that impair folic acid metabolism. Furthermore, emerging evidence suggests that optimal folate status may support fertility and reduce the risk of other pregnancy complications such as preeclampsia and miscarriage, though the strongest evidence remains for NTD prevention. Thus, the use of vitamin B9 (5-MTHF) to support the female reproductive system is both scientifically validated and widely implemented in clinical practice.

More about Vitamin B9 (methyltetrahydrofolate)
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Other ingredients that support Female Reproductive System

7-hydroxymatairesinol (HMR)
amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
Furostanols
formononetin
Fatty acids
False Unicorn Root
Ginsenosides
Goat's rue
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
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Products containing Vitamin B9 (methyltetrahydrofolate)

We currently have no products on Caring Sunshine that contain this ingredient.