Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Secoisolariciresinol diglycoside (SDG) is a plant lignan predominantly found in flaxseed. After ingestion, SDG is converted by intestinal bacteria into the mammalian lignans enterodiol and enterolactone, which possess phytoestrogenic activity. Several studies have investigated the effects of flaxseed and its lignans on the female reproductive system, particularly in relation to hormone modulation and menstrual health.

Clinical and preclinical research suggests that SDG may influence estrogen metabolism and modulate circulating hormone levels. Some small human trials and animal studies have indicated that flaxseed consumption can lengthen the luteal phase of the menstrual cycle and reduce the risk of anovulatory cycles, potentially supporting reproductive health. Additionally, SDG's phytoestrogenic properties have led to interest in its role in alleviating menopausal symptoms such as hot flashes, though the evidence remains mixed.

While these findings show promise, the overall evidence is still limited, with relatively few high-quality, large-scale clinical trials directly evaluating isolated SDG for specific female reproductive outcomes. Most available data are from studies using whole flaxseed or flaxseed extracts, making it difficult to attribute effects solely to SDG. Thus, there is moderate scientific support (rated 3/5) for SDG's role in supporting the female reproductive system, primarily through hormone modulation, but further research is needed to clarify its efficacy and mechanisms.

More about Secoisolariciresinol-diglycoside
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Other ingredients that support Female Reproductive System

7-hydroxymatairesinol (HMR)
amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
Furostanols
formononetin
Fatty acids
False Unicorn Root
Ginsenosides
Goat's rue
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
Vervain

Other body systems supported by Secoisolariciresinol-diglycoside

Estrogen
Female Reproductive System
Heart

Products containing Secoisolariciresinol-diglycoside

We currently have no products on Caring Sunshine that contain this ingredient.