Evidence supporting the use of: Formononetin
For the body system: Female Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Formononetin is an isoflavone compound primarily found in plants such as red clover (Trifolium pratense). Its use to support the female reproductive system is primarily based on traditional herbal medicine rather than robust scientific validation. Historically, red clover, which contains formononetin among other phytoestrogens, has been used in various cultures to alleviate menopausal symptoms, such as hot flashes and night sweats, due to its mild estrogenic effects. These traditional uses are rooted in the observation that certain plants can mimic the activity of estrogen in the body, which might help in hormonal balance during menopause or other times of hormonal fluctuation.
While some preliminary scientific studies have investigated the estrogen-like activity of formononetin and other red clover isoflavones, the direct evidence supporting its efficacy for female reproductive health is limited and not definitive. Most clinical trials have focused on red clover extracts rather than isolated formononetin, and results have been mixed regarding their effectiveness for menopausal symptoms. Therefore, while tradition supports the use of formononetin-rich plants for female reproductive health, strong scientific evidence is lacking, and more research is needed to confirm its safety and effectiveness.
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lactobacillus gasseri
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Other body systems supported by formononetin
EstrogenFemale Reproductive System
Heart
Ovaries
Reproductive System