Evidence supporting the use of: Chastetree
For the body system: Female Reproductive System
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Chastetree (Vitex agnus-castus), also known as Vitex or chasteberry, has a long history of use in traditional herbal medicine, particularly for supporting female reproductive health. Its primary traditional uses include relief from symptoms of premenstrual syndrome (PMS), regulation of menstrual cycles, and alleviation of menopausal symptoms. Modern scientific research has provided moderate evidence to support these traditional uses. Several randomized controlled trials and meta-analyses suggest that Chastetree extract can significantly reduce PMS symptoms such as breast pain, irritability, and mood swings. The proposed mechanism involves modulation of prolactin levels via dopaminergic activity, which may help address menstrual irregularities and certain PMS symptoms. There is also some evidence suggesting benefit for mild hyperprolactinemia and cyclic mastalgia.
However, while the evidence is promising, the quality of studies varies, and more large-scale, high-quality research is needed to confirm optimal dosing and long-term safety. Chastetree is generally considered safe for most women when used at recommended doses, but it may interact with hormone-related medications or conditions. In summary, Chastetree’s use for supporting the female reproductive system is supported by both tradition and a moderate level of scientific evidence, particularly for PMS and menstrual regulation.
Other ingredients that support Female Reproductive System
7-hydroxymatairesinol (HMR)amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
Furostanols
formononetin
Fatty acids
False Unicorn Root
Ginsenosides
Goat's rue
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
Vervain
Other body systems supported by Chastetree
BreastsEstrogen
Female Reproductive System
Glandular System
Hypothalamus
Ovaries
Pituitary
Pituitary (anterior)
Progesterone
Reproductive System
Uterus