Evidence supporting the use of: Angelica
For the body system: Female Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Angelica (commonly referring to Angelica sinensis, also known as Dong Quai) has a long history of use in traditional Chinese medicine for supporting female reproductive health. It has been traditionally used to help regulate menstrual cycles, alleviate menstrual cramps, and support overall reproductive health. Historical texts document its use in formulas for menstrual irregularities, menopausal symptoms, and as a general “female tonic.” The root is believed to modulate estrogenic activity and improve blood circulation, which are considered beneficial for gynecological health in traditional systems.
While there is some laboratory and animal research suggesting potential estrogenic effects and possible impact on smooth muscle relaxation, robust clinical trials in humans are lacking. Reviews of scientific literature conclude that while traditional use is strong, there is insufficient high-quality clinical evidence to fully validate these effects by modern standards. Most available studies are small, not well-controlled, or focus on multi-herb formulations, making it difficult to isolate the effect of Angelica alone. Thus, the support for its use in female reproductive health is primarily based on tradition, with some preliminary but inconclusive scientific interest.
Other ingredients that support Female Reproductive System
7-hydroxymatairesinol (HMR)amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
Furostanols
formononetin
Fatty acids
False Unicorn Root
Ginsenosides
Goat's rue
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
Vervain
