Evidence supporting the use of: Polyphenols
For the health condition: Fat Metabolism (poor)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols, a diverse group of phytochemicals found abundantly in fruits, vegetables, tea, coffee, and wine, have been the focus of numerous studies regarding their effects on fat metabolism. Scientific evidence suggests that certain polyphenols, such as catechins (from green tea), resveratrol (from grapes), and flavonoids (from various plant sources), can influence lipid metabolism and energy expenditure. Mechanistically, polyphenols are believed to activate AMP-activated protein kinase (AMPK), enhance mitochondrial biogenesis, and modulate genes involved in adipogenesis and lipolysis. For example, green tea catechins have been shown in some randomized controlled trials to increase fat oxidation and improve body composition, especially when combined with caffeine. Animal studies also demonstrate that polyphenols can reduce fat accumulation and improve lipid profiles. However, while there is a growing body of preclinical and some human evidence, the effects are generally modest and may vary depending on the type and dose of polyphenol, as well as individual metabolic differences. Systematic reviews and meta-analyses indicate potential benefits, but larger, long-term human studies are needed for definitive conclusions. Overall, polyphenols are scientifically studied for their role in supporting fat metabolism, with a moderate but promising evidence base.

More about polyphenols
More about Fat Metabolism (poor)