Evidence supporting the use of: Glucomannan
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Glucomannan is a soluble dietary fiber extracted from the root of the konjac plant (Amorphophallus konjac). Its use in supporting fat metabolism is primarily based on scientific studies rather than traditional medicine. Glucomannan is believed to aid weight management and, indirectly, fat metabolism by promoting satiety, reducing appetite, and slowing the absorption of dietary fat and carbohydrates. Some clinical trials have shown that supplementation with glucomannan, when combined with a calorie-restricted diet, can lead to modest reductions in body weight and body fat. A few studies suggest that glucomannan may help lower total cholesterol and LDL cholesterol, markers often associated with fat metabolism and cardiovascular risk.
However, the mechanism is not a direct effect on fat metabolism per se, but rather an indirect one through its impact on dietary intake and nutrient absorption. The European Food Safety Authority (EFSA) has approved glucomannan for weight loss in the context of an energy-restricted diet, but the evidence for a direct effect on enhancing fat metabolism is limited. The overall quality of supporting evidence is moderate, with some meta-analyses showing small but significant effects and others indicating inconsistent results. Therefore, while there is some scientific validation for glucomannan’s role in weight management, its direct effect on fat metabolism is less well established, justifying a moderate evidence rating.
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
Other health conditions supported by glucomannan
Appetite (excessive)Cholesterol (high)
Diabetes
Fat Metabolism (poor)
Indigestion
Metabolic Syndrome
Sugar Cravings
Triglycerides (high)
Weight Loss
