Evidence supporting the use of: Superoxide Dismutase
For the body system: Eyes

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Superoxide Dismutase (SOD) is an antioxidant enzyme that catalyzes the dismutation of superoxide radicals into oxygen and hydrogen peroxide, thereby protecting cells from oxidative damage. The eye is particularly susceptible to oxidative stress due to constant exposure to light and high metabolic activity, which has led researchers to investigate antioxidants like SOD in ocular health. Animal studies and some limited human data suggest that SOD levels are important in protecting retinal cells and the lens from oxidative injury, which is implicated in conditions such as age-related macular degeneration (AMD) and cataract formation. For example, decreased SOD activity has been observed in the lenses of patients with cataracts, and experimental models show that enhancing SOD activity can reduce damage from oxidative stress in ocular tissues. However, the evidence that oral or topical SOD supplementation directly improves eye health in humans is limited and mixed. Issues such as SOD's bioavailability and delivery to ocular tissues remain challenges. Consequently, while there is scientific rationale and some preclinical evidence supporting a protective role for SOD in eye health, robust clinical trials demonstrating efficacy of SOD supplementation for eye conditions are lacking. Therefore, the scientific support for using SOD to support the eye body system is modest and not yet definitive.

More about Superoxide Dismutase
More about Eyes

Products containing Superoxide Dismutase

We currently have no products on Caring Sunshine that contain this ingredient.