Evidence supporting the use of: Riboflavin (B2)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Riboflavin (vitamin B2) has scientific support for its role in eye health, though the evidence is moderate rather than overwhelming. Riboflavin is essential for maintaining the normal function of mucous membranes, including those in the eyes, and acts as a coenzyme in numerous oxidation-reduction reactions in the body. Riboflavin deficiency can lead to ocular symptoms such as photophobia, excessive tearing, itching, and vascularization of the cornea, as well as the development of cataracts. Several observational studies suggest that adequate riboflavin intake may reduce the risk of cataract formation. For example, a study published in the American Journal of Clinical Nutrition noted an association between higher dietary intake of riboflavin and a lower risk of age-related cataracts. However, interventional trials are limited and results are not always consistent.

The mechanism by which riboflavin may protect the eyes involves its role in glutathione metabolism and antioxidant defense systems, which help counteract oxidative stress—a key factor in cataract development. Due to its recognized role in preventing deficiency-related eye symptoms and potential for reducing cataract risk, riboflavin is included in several eye health supplements.

In summary, while riboflavin’s importance for eye health is well established in the context of deficiency prevention, its broader use for supporting eye health in people with adequate dietary intake has moderate scientific support, primarily related to cataract risk reduction.

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