Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pycnogenol is a standardized extract from the bark of the French maritime pine tree (Pinus pinaster). Scientific evidence supports its use for eye health, particularly in addressing microvascular circulation issues such as diabetic retinopathy and retinal edema. Several randomized controlled trials and clinical studies have shown that Pycnogenol may help improve capillary integrity and reduce retinal edema, which can benefit individuals with early diabetic retinopathy. The proposed mechanisms include antioxidant effects, inhibition of platelet aggregation, and strengthening of blood vessel walls, all of which can help protect delicate ocular tissues from damage due to oxidative stress and microvascular leakage.

For example, a 2012 study published in Journal of Ocular Pharmacology and Therapeutics found that supplementation with Pycnogenol improved retinal blood flow and reduced retinal edema in diabetic patients. Another study in Phytotherapy Research (2001) reported improvements in visual acuity and reduction in retinal swelling. However, while these studies are promising, sample sizes are often small, and further research is needed to fully establish long-term benefits and optimal dosages. There is insufficient evidence to recommend Pycnogenol for other eye conditions, such as age-related macular degeneration or glaucoma. In summary, there is scientific support, though not conclusive, for using Pycnogenol to support microvascular health in the eyes, particularly in the context of diabetic complications.

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