Evidence supporting the use of: Proanthocyanidins
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Proanthocyanidins, a class of polyphenolic compounds found in foods such as grapes, berries, and cocoa, are known for their potent antioxidant properties. Their use to support eye health is primarily based on their ability to combat oxidative stress, which plays a significant role in the development of age-related eye disorders such as cataracts and macular degeneration. Some scientific studies, including small clinical trials and animal studies, suggest that proanthocyanidins may protect retinal cells and capillaries, contributing to the maintenance of visual function. For example, grape seed extract, which is rich in proanthocyanidins, has demonstrated protective effects against oxidative damage in ocular tissues in preclinical models. However, robust, large-scale human clinical trials directly linking proanthocyanidin supplementation to improved eye health or prevention of eye disease are limited. As such, while there is some scientific rationale and early evidence supporting their use for eye health, the overall quality and quantity of evidence remain moderate at best, justifying a middling rating. More rigorous clinical research is needed to definitively establish efficacy.
Other ingredients that support Eyes
acetyl l-carnitinealgal oil
alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
l-carnosine
l-taurine
lutein
mackerel
mannitol
marine lipid
melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
sardines
shrimp
spinach
tomato
triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
water
mulberry
zeaxanthin
zinc
chickweed
morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
Avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
Bioflavonoids
Bee products
Barbary matrimony vine
Crocin
Carnosine
Cod Liver Oil
Cyanidin
Cornflower
Cantaloupe
Chinese Ligustrum berry
Cornus
Carotene (unspecified)
Crocetin
Cocklebur
Crypthecodinium
Celosia
Capsanthin
Currant
Dunaliella salina
Docosahexaenoic Acid
Dunaliella
Egg
Ergothioneine
Eyebright
Eicosapentaenoic Acid
Fruit
Flavonoids
Fish
Fatty acids
Fagopyrum
Flavoglycosides
fibroblast growth factor
Gac
Ginkgo Flavone Glycoside
Glutathione
Gamma-carotene
Rose
Squid
Squash
Other body systems supported by Proanthocyanidins
ArteriesBlood
Capillaries
Circulatory System
Eyes
Gastrointestinal Tract
Gums
Heart
Immune System
Skin
Urinary System
Veins