Evidence supporting the use of: Leucoanthocyanins
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Leucoanthocyanins, also known as proanthocyanidins or condensed tannins, are a class of polyphenolic compounds found in many plants, notably in grape seeds, pine bark, and certain fruits. There is scientific evidence to support their use in supporting eye health, particularly regarding the prevention or mitigation of oxidative stress-related eye conditions. Several studies have explored the antioxidant properties of leucoanthocyanins, highlighting their ability to neutralize free radicals and reduce oxidative damage in ocular tissues. This is relevant since oxidative stress is a known contributing factor in the development of eye disorders such as age-related macular degeneration (AMD) and cataracts.

Some research, including animal studies and small clinical trials, suggests that supplementation with proanthocyanidins can improve retinal health and visual function, and may help maintain the integrity of blood vessels in the eyes. The most commonly cited sources are grape seed extract and bilberry extract, both rich in leucoanthocyanins, which have been shown to support capillary strength and decrease vascular permeability—potentially beneficial for retinal health.

However, while the antioxidant and vascular-protective effects are well-documented in laboratory and animal studies, human clinical data specifically linking leucoanthocyanin supplementation to significant improvements in eye health remain limited. Thus, while there is a scientific rationale and some preliminary evidence, more robust clinical trials are needed to confirm efficacy.

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Other body systems supported by Leucoanthocyanins

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gums
Heart
Skin
Veins

Products containing Leucoanthocyanins

We currently have no products on Caring Sunshine that contain this ingredient.