Evidence supporting the use of: Flavonones (unspecified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavanones are a subclass of flavonoids, naturally occurring compounds found in citrus fruits and other plants. There is a growing body of scientific evidence suggesting that flavanones may support eye health due to their antioxidant and anti-inflammatory properties. Oxidative stress and inflammation are key contributors to various eye disorders, including age-related macular degeneration (AMD), cataracts, and diabetic retinopathy.

Flavanones such as hesperidin, naringenin, and eriodictyol have demonstrated the ability to scavenge free radicals and reduce oxidative damage in ocular tissues in preclinical studies. Some animal and cell-based studies indicate that these compounds may help protect retinal cells and improve microcirculation within the eye. Epidemiological studies have associated higher intake of flavonoid-rich foods (including flavanones) with a reduced risk of some age-related eye diseases.

However, while the underlying mechanisms are biologically plausible and some early research is promising, there are relatively few well-controlled human clinical trials specifically examining flavanones’ direct benefits for eye health. Most evidence comes from broader studies of flavonoids or from laboratory models. Therefore, the scientific support for the use of flavanones to support the eyes is moderate, and further clinical research is warranted to validate these effects in humans.

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