Evidence supporting the use of: Flavones (various)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavones, a subclass of flavonoids found abundantly in various fruits, vegetables, and medicinal plants, have been scientifically studied for their potential benefits to eye health. Several preclinical and clinical studies suggest that flavones—such as luteolin and apigenin—exhibit antioxidant, anti-inflammatory, and neuroprotective properties, which may help protect ocular tissues from oxidative stress and degenerative changes associated with aging and common eye diseases. For example, oxidative damage is a known contributory factor in cataract formation and age-related macular degeneration (AMD). Flavones have been shown to scavenge free radicals, reduce inflammation, and improve vascular health, all of which are relevant to maintaining retinal and lens health. Population-based studies have indicated that diets rich in flavonoids, including flavones, are associated with a lower risk of developing cataracts and AMD. However, while the mechanistic and epidemiological evidence is promising, large-scale, long-term randomized controlled trials directly linking flavone supplementation with reduced incidence or progression of specific eye diseases are still limited. Thus, the scientific evidence supports their role, particularly as part of a flavonoid-rich diet, but more rigorous clinical research is needed before making definitive recommendations.

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