Synopsis

Source of validity: Scientific
Rating (out of 5): 1

D-Aspartic Acid (DAA) is an amino acid that has gained popularity as a supplement, particularly among athletes and bodybuilders, for its purported effects on exercise performance and testosterone production. The scientific rationale stems from early studies suggesting that DAA could increase testosterone levels, which might enhance muscle growth, strength, and exercise performance. However, subsequent research has cast significant doubt on these claims. Several controlled studies in healthy men have shown that DAA supplementation does not consistently increase testosterone levels or improve exercise performance. In fact, some research has found no significant differences in muscle strength, muscle mass, or endurance between those taking DAA and those taking a placebo. A 2017 systematic review concluded that DAA supplementation does not enhance exercise-induced adaptations in resistance-trained men. Thus, while DAA is marketed for exercise support, the scientific evidence is weak and inconsistent, and the overall effect size is negligible. There is little to no traditional or historical use of DAA for exercise, as its popularity is a recent phenomenon tied to supplement marketing. In summary, scientific support for D-aspartic acid as an exercise aid is minimal, warranting a low evidence rating.

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