Evidence supporting the use of: Vitamin D
For the health condition: Estrogen (low)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has a scientifically supported, but still emerging, connection to estrogen levels, particularly in women. Several studies have shown that vitamin D may play a role in regulating the synthesis and activity of sex hormones, including estrogen. One mechanism is through the presence of vitamin D receptors (VDR) in ovarian tissue; vitamin D can influence the expression of genes involved in estrogen production. Observational studies have reported a correlation between adequate vitamin D levels and higher estrogen concentrations, especially in premenopausal and postmenopausal women. Some interventional studies suggest that vitamin D supplementation may increase estradiol (a form of estrogen) in women with low baseline levels, though findings are inconsistent and effects are often modest.

However, the evidence is not robust enough to recommend vitamin D as a primary treatment for low estrogen. Most research focuses on bone health, where both vitamin D and estrogen are important, rather than direct treatment of estrogen deficiency itself. There is no established clinical guideline recommending vitamin D solely for estrogen support, but it is sometimes considered as an adjunct in managing menopausal symptoms or supporting reproductive health due to its broader endocrine effects. Therefore, while there is scientific plausibility and some supporting data, the evidence remains limited (rating: 2/5), and further high-quality clinical trials are needed to clarify the relationship.

More about vitamin D
More about Estrogen (low)

Other health conditions supported by vitamin D

Acne
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anorexia
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Autism
Autoimmune Disorders
Backache
Birth Defects (prevention)
Body Building
Broken Bones
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Contagious Diseases
Convalescence
Convulsions
Cramps (menstrual)
Cramps and Spasms
Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fatigue
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Irritable Bowel Syndrome
Itching
Knees (weak)
Leaky Gut Syndrome
Leprosy
Lesions
Leukemia
Lou Gehrig's Disease
Lupus
Lymphoma
Melanoma
Memory and Brain Function
Menopause
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Myasthenia Gravis
Nephritis
Nerve Damage
Nervous Exhaustion
Numbness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pain (general remedies for)
Pancreatitis
Paralysis
Parkinson's Disease
Peripheral Neuropathy
PMS (general)
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prostatitis
Psoriasis
Rheumatoid Arthritis
Schizophrenia
Sciatica
Seasonal Affective Disorder
Senility
Tuberculosis