Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Equol is a non-steroidal estrogen produced in the gut from the metabolism of the soy isoflavone daidzein by specific intestinal bacteria. Its use to support low estrogen states, such as in menopause, is primarily justified by scientific evidence rather than traditional medicine. Several clinical studies have demonstrated that equol can bind to estrogen receptor beta and exert estrogenic effects, which may help alleviate symptoms associated with low estrogen, such as hot flashes, night sweats, and bone loss. Double-blind, placebo-controlled trials have shown that equol supplementation can reduce menopausal symptoms in women, particularly in those who are "equol non-producers" (individuals whose gut flora do not naturally produce equol from dietary isoflavones). However, equol is not a replacement for endogenous estrogen and does not fully mimic all estrogenic actions. The evidence is strongest for its ability to reduce vasomotor symptoms and improve some markers of bone health, but it is less robust for other low-estrogen complications. The proprietary forms of equol are standardized and bioavailable, offering a more predictable effect than dietary soy alone. Overall, while equol shows promise and is supported by moderate-quality scientific studies, it is not considered a first-line therapy for low estrogen but may be a useful adjunct in managing certain menopausal symptoms.

More about Equol (proprietary)
More about Estrogen (low)

Other ingredients used for Estrogen (low)

Other health conditions supported by Equol (proprietary)

Products containing Equol (proprietary)

Nature's Sunshine Equolibrium™