Evidence supporting the use of: Sage oil
For the body system: Estrogen
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Sage oil (Salvia officinalis) has a long history of traditional use for supporting women's health, particularly in relation to menopausal symptoms that are connected to estrogen fluctuations, such as hot flashes and night sweats. Herbalists have often recommended sage in various forms—including teas, extracts, and essential oils—for its reputed ability to balance hormones and alleviate symptoms associated with low estrogen. The traditional rationale is based on observations that sage may have mild estrogenic effects, possibly due to its phytoestrogen content. However, robust scientific evidence validating these effects is limited.
A few small clinical studies and animal research suggest that sage extracts may help reduce the frequency and severity of hot flashes in menopausal women, but these studies generally use oral extracts, not essential oil. The exact mechanisms are not well understood, and there is no clear evidence that sage oil directly increases estrogen levels or exerts clinically significant estrogenic activity. Safety concerns also exist, as sage oil contains thujone, which can be neurotoxic in high doses. While traditional use is strong, scientific validation is limited and more research is needed to establish efficacy and safety for this specific purpose.
Other ingredients that support Estrogen
7-hydroxymatairesinol (HMR)black cohosh
chaste tree
d-glucarate
daidzin
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
fennel
flaxseed
genistein
genistin
ginseng
HMR lignan
hops
indole-3-carbinol
licorice root
lignans
maca
sage
secoisolariciresinol diglucoside
soybean
spearmint leaf
vitamin B6
vitamin E
wild yam
red clover
anise
yarrow
dioscorea
Equol (proprietary)
soy isoflavones
27-deoxyactein
4-Hydroxyandrostenedione
8-Prenylnaringenin
Agnuside
Anti-aromatase
Brassica
Bugbane
biochanin
Barbasco
Cohosh
Clary sage
Cruciferous
Casticin
Coumesterol
DHEA
Daidzein
Dong Quai
Diosgenin
formononetin
Ginsenosides
Glycetein
Glabridin
Isoflavones
Soy Protein