Evidence supporting the use of: Ovary
For the body system: Estrogen
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Ovary extract has been used in both traditional medicine and modern science to support estrogen-related body systems, particularly in the context of hormone replacement therapies and menopausal symptom management. The primary scientific rationale is that ovary extracts contain naturally occurring estrogens and other ovarian hormones. In the early to mid-20th century, before the advent of synthetic estrogens, ovarian tissue extracts were used therapeutically to alleviate symptoms of menopause, such as hot flashes and vaginal atrophy. Research from the 1930s and 1940s demonstrated that these extracts could provide measurable estrogenic effects in both animal models and human subjects. However, with the advent of purified and synthetic hormones, the use of whole ovary extracts has declined significantly due to variability in potency and concerns about safety and standardization.
Modern scientific evidence supports the principle that ovarian tissue is a source of estrogens, and thus the use of ovary extracts to support estrogen body systems is grounded in biology. However, few contemporary studies directly assess the efficacy or safety of ovary extracts compared to modern hormone therapies. Regulatory agencies now favor precisely dosed and purified estrogens rather than tissue extracts. Nonetheless, the historical and scientific use of ovary extract for estrogen support is well documented, justifying a high evidence rating, though current clinical practice has moved beyond this approach.
Other ingredients that support Estrogen
7-hydroxymatairesinol (HMR)black cohosh
chaste tree
d-glucarate
daidzin
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
fennel
flaxseed
genistein
genistin
ginseng
HMR lignan
hops
indole-3-carbinol
licorice root
lignans
maca
sage
secoisolariciresinol diglucoside
soybean
spearmint leaf
vitamin B6
vitamin E
wild yam
red clover
anise
yarrow
dioscorea
Equol (proprietary)
soy isoflavones
27-deoxyactein
4-Hydroxyandrostenedione
8-Prenylnaringenin
Agnuside
Anti-aromatase
Brassica
Bugbane
biochanin
Barbasco
Cohosh
Clary sage
Cruciferous
Casticin
Coumesterol
DHEA
Daidzein
Dong Quai
Diosgenin
formononetin
Ginsenosides
Glycetein
Glabridin
Isoflavones
Soy Protein