Evidence supporting the use of: Anti-aromatase
For the body system: Estrogen
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Anti-aromatase agents are used to support the estrogen body system primarily due to substantial scientific evidence. Aromatase is an enzyme responsible for the conversion of androgens (such as testosterone) to estrogens (such as estradiol) in the body. In certain clinical contexts, such as estrogen receptor-positive breast cancer, anti-aromatase drugs (commonly called aromatase inhibitors) are prescribed to lower estrogen levels, thereby slowing or preventing tumor growth that depends on estrogen. Examples of these pharmaceuticals include anastrozole, letrozole, and exemestane.
In addition to oncology, anti-aromatase agents are sometimes investigated for male hypogonadism, gynecomastia, and infertility, where excess estrogen is implicated. They are also of interest in the context of bodybuilding and hormone therapy, where they may be used off-label to prevent estrogenic side effects of anabolic steroid use.
There is robust clinical trial and mechanistic evidence supporting the efficacy of anti-aromatase medications in lowering estrogen levels. However, their use outside of well-defined clinical indications should be approached with caution due to potential side effects, including bone loss, lipid changes, and musculoskeletal symptoms. In summary, anti-aromatase agents are scientifically validated for the modulation of the estrogen system, particularly in specific medical indications.
Other ingredients that support Estrogen
7-hydroxymatairesinol (HMR)black cohosh
chaste tree
d-glucarate
daidzin
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
fennel
flaxseed
genistein
genistin
ginseng
HMR lignan
hops
indole-3-carbinol
licorice root
lignans
maca
sage
secoisolariciresinol diglucoside
soybean
spearmint leaf
vitamin B6
vitamin E
wild yam
red clover
anise
yarrow
dioscorea
Equol (proprietary)
soy isoflavones
27-deoxyactein
4-Hydroxyandrostenedione
8-Prenylnaringenin
Agnuside
Anti-aromatase
Brassica
Bugbane
biochanin
Barbasco
Cohosh
Clary sage
Cruciferous
Casticin
Coumesterol
DHEA
Daidzein
Dong Quai
Diosgenin
formononetin
Ginsenosides
Glycetein
Glabridin
Isoflavones
Soy Protein
Other body systems supported by Anti-aromatase
EstrogenMale Reproductive System
Prostate
Testes
Testosterone