Evidence supporting the use of: L-tyrosine
For the body system: Epinephrine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-tyrosine is an amino acid that serves as a precursor for the synthesis of catecholamines, including dopamine, norepinephrine, and epinephrine (adrenaline). The rationale for using L-tyrosine to support the "epinephrine body system" (i.e., the body's stress response or adrenal function) is based on its biochemical role in catecholamine biosynthesis. Several scientific studies have examined whether tyrosine supplementation can influence catecholamine levels and improve cognitive or physical performance under stress, such as cold, sleep deprivation, or military training.

Research in humans has shown that under acute stress conditions—where catecholamine demand is increased—tyrosine supplementation can help maintain cognitive performance and mood, possibly by supporting catecholamine synthesis when the body's stores might otherwise become depleted. However, evidence for its routine use in healthy individuals or outside of acute stress scenarios is less robust, and there is no strong evidence that it directly increases epinephrine levels under normal circumstances.

Overall, the scientific evidence supports a role for L-tyrosine in supporting catecholamine synthesis during stress, with most research noting benefits in highly demanding or stressful situations rather than for general, everyday use. The evidence is moderate (rated 3/5) and specific to certain contexts, rather than being universally strong or broadly applicable.

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More about Epinephrine