Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phytoecdysteroids are naturally occurring plant sterols structurally similar to insect molting hormones. The most widely studied phytoecdysteroid is 20-hydroxyecdysone, commonly found in plants such as Rhaponticum carthamoides (leuzea/maral root). There is limited scientific evidence suggesting phytoecdysteroids may support enhanced energy, stamina, or physical performance. A small number of animal studies and a handful of preliminary human trials have investigated their potential to increase physical work capacity or reduce fatigue, possibly by improving protein synthesis or mitochondrial function. However, these studies are typically small, short-term, and often use extracts with varying concentrations of phytoecdysteroids, making it difficult to draw firm conclusions.

Their use as energy boosters is not rooted in long-standing traditional medicine systems, but rather in modern sports nutrition and supplementation, where they are marketed for purported adaptogenic and ergogenic effects. The overall quality and quantity of human clinical evidence is low; most studies show modest or no significant effects on physical energy or endurance. Thus, while there is some scientific investigation, the evidence remains weak and not robust enough to firmly support their use for treating lack of energy.

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