Evidence supporting the use of: Cannabis
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabis has been investigated for its potential in supporting or treating dysmenorrhea (menstrual pain), with some scientific basis for its use, though current evidence is limited and of variable quality. Historically, cannabis has been mentioned in various cultures as a remedy for gynecological complaints, including menstrual pain, but most modern interest is driven by scientific inquiry.

Phytocannabinoids in cannabis, such as THC and CBD, interact with the body’s endocannabinoid system, which plays a role in pain modulation and inflammation. Preclinical studies and some observational reports suggest that cannabinoids may help reduce pain, muscle spasms, and inflammation, which are key contributors to dysmenorrhea. Surveys of patients with chronic pelvic pain or endometriosis frequently report self-medication with cannabis, and many of these individuals describe perceived benefits for menstrual pain specifically.

However, high-quality clinical trials directly evaluating cannabis for dysmenorrhea are lacking. The available scientific evidence comes mainly from extrapolation of cannabis’s effects in other chronic pain conditions and from small observational studies or surveys, which are subject to bias. The American College of Obstetricians and Gynecologists and similar bodies acknowledge the potential but emphasize the need for well-controlled clinical trials. Thus, while there is a plausible mechanism and anecdotal support, rigorous scientific validation for cannabis in dysmenorrhea is currently insufficient, justifying a moderate evidence rating.

More about Cannabis
More about Dysmenorrhea

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