Evidence supporting the use of: Calotropis gigantea
For the health condition: Dysmenorrhea
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Calotropis gigantea, commonly known as Crown Flower or Giant Milkweed, has been used in traditional medicine systems, particularly in Ayurveda and folk medicine in South Asia, for a variety of ailments including dysmenorrhea (painful menstruation). Historical texts and ethnobotanical surveys document its use as an emmenagogue (an agent that stimulates menstrual flow) and in alleviating menstrual cramps. Various parts of the plant, especially the roots and leaves, have been prepared as decoctions or poultices for women experiencing menstrual pain.
Regarding scientific validation, there is limited direct research evaluating the efficacy of Calotropis gigantea specifically for dysmenorrhea. Some laboratory studies have demonstrated that extracts from the plant exhibit anti-inflammatory, analgesic, and antispasmodic properties in animal models or in vitro, all of which could theoretically contribute to relief of menstrual pain. However, these findings are preliminary and not specific to dysmenorrhea in humans. No high-quality clinical trials have been published to confirm its effectiveness for this use.
In summary, the use of Calotropis gigantea for dysmenorrhea is primarily justified by traditional knowledge, with some supportive but indirect pharmacological evidence. The overall strength of evidence is low (rated 2/5) due to the lack of clinical studies directly linking the plant to relief of menstrual pain in humans.
Other ingredients used for Dysmenorrhea
AbutaAchyranthes
Actaea spicata
Aerva lanata
Agnuside
Agrimonia pilosa
Albizia
Alchemilla
Aletris
alpha-linolenic acid (ALA)
ambergris
anamu
Anemone
Angelica
anise
Anserina
Arisaema
Ashoka
avens
bethroot
black cohosh
Blepharis
blue cohosh
Boerhavia diffusa
Boswellia
calcium
Calendula
Calotropis gigantea
chamomile
chaste tree
cohosh
Corydalis
Cyathula
Didymocarpus
dioscorea
dong quai
dong quai root
EPA (eicosapentaenoic acid)
Erythropalum scandens
Euphorbia
Eupolyphaga sinensis
evening primrose oil
fennel
fish oil
gastrodia
ginger
Labisia pumila
Lady's Mantle
Lophira lanceolata
magnesium
Mezoneuron benthamianum
Montanoa tomentosa
Motherwort
omega-3 fatty acids
parsley
passionflower
Pennyroyal
peony
Peppermint
phytocannabinoids
Phytoestrogens
poppy
Pulsatilla
rue
Semecarpus anacardium
shepherd's purse
Trichosanthes
Viburnum
vitamin B6
vitamin E
Vitex Agnus-Castus
Wild yam
Other health conditions supported by Calotropis gigantea
Abdominal PainAbrasions
Abscesses
Afterbirth Pain
Anal Fistula or Fissure
Antibiotics (alternatives to)
Bites and Stings
Boils
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cuts
Diarrhea
Digestion (poor)
Dysmenorrhea
Ear Infection or Earache
Eczema
Edema
Eye Infections
Fever
Glands (swollen lymph)
Inflammation
Injuries
Insect Repellant
Itching
Jaundice (adults)
Lymph Nodes or Glands (swollen)
Menstrual Irregularity
Pain (general remedies for)
Parasites (general)
Parasites (nematodes, worms)
Rashes and Hives
Scars / Scar Tissue
Scratches and Abrasions
Snake Bite
Sunburn
