Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Holarrhena, particularly Holarrhena antidysenterica, has a long history of traditional use in the treatment of dysentery and other gastrointestinal disorders in Ayurvedic, Unani, and other traditional medicine systems in South Asia. The seeds and bark (often called "Kutaja" in Ayurveda) are commonly used to treat amoebic and bacillary dysentery. Ancient Ayurvedic texts, such as the Charaka Samhita and Sushruta Samhita, mention its utility for "Atisara" (diarrhea) and "Pravahika" (dysentery). The plant is believed to have astringent, anti-inflammatory, and antimicrobial properties. Modern pharmacological studies have provided some support for these traditional claims. Extracts of Holarrhena antidysenterica have shown antimicrobial activity against various pathogens, including Shigella and Escherichia coli, which are common causes of dysentery. Some animal studies and small clinical trials suggest benefit in reducing symptoms and controlling infection. However, the quality and quantity of rigorous clinical evidence is limited, and most data are from preclinical research or uncontrolled trials. Thus, while traditional use is well established and there is some scientific rationale, large, well-designed clinical studies are lacking. The evidence level is moderate, primarily rooted in tradition with preliminary scientific support.

More about Holarrhena (unspecified)
More about Dysentery

Other ingredients used for Dysentery

Other health conditions supported by Holarrhena (unspecified)

Products containing Holarrhena (unspecified)