Evidence supporting the use of: Ginkgolide C
For the health condition: Dizziness

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ginkgolide C is a terpene lactone found in the leaves of Ginkgo biloba. The use of Ginkgo biloba extracts, which contain ginkgolide C among other constituents, to address dizziness is rooted primarily in traditional and herbal medicine practices, especially in East Asia and, more recently, in Western herbal supplement markets. Historically, Ginkgo has been used to support cognitive function and improve circulation, including claims of alleviating vertigo and dizziness, often attributed to its effects on blood flow and neuroprotection.

However, the evidence specifically supporting ginkgolide C, as an isolated compound, for the treatment or management of dizziness is limited. Most clinical studies have focused on standardized Ginkgo biloba extracts (such as EGb 761), which contain multiple active components, including flavonoids and several ginkgolides. Some studies suggest that these extracts may help with vertigo or dizziness, particularly when related to vascular insufficiency or age-related cognitive decline, but the results are mixed and often attributed to the extract as a whole, rather than to ginkgolide C alone.

In summary, while ginkgolide C is a component of traditional herbal remedies for dizziness via Ginkgo biloba extracts, there is insufficient direct scientific evidence to support its isolated use for this condition. The traditional use and some indirect clinical evidence for Ginkgo biloba extracts justify a modest rating.

More about Ginkgolide C
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