Evidence supporting the use of: Lipids (unspecified)
For the health condition: Dermatitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Lipids, particularly in the form of topical emollients and certain oral supplements (such as essential fatty acids), have scientific backing for their use in supporting the treatment of dermatitis. The skin barrier in conditions like atopic dermatitis is often disrupted, leading to increased transepidermal water loss and vulnerability to irritants. Topical lipid-based formulations—containing ceramides, cholesterol, and free fatty acids—help restore the skin’s barrier function and reduce symptoms of dryness, irritation, and inflammation. Several randomized controlled trials and meta-analyses have shown that topical lipid-rich moisturizers can improve clinical outcomes in patients with dermatitis, especially atopic dermatitis.
Oral supplementation with certain lipids, notably omega-3 and omega-6 fatty acids (such as evening primrose oil and borage oil), has also been investigated. While some studies indicate modest benefits in symptom reduction, the evidence is less robust and more variable compared to topical application. Leading guidelines recommend regular use of emollients containing physiological lipids as a cornerstone of dermatitis management. However, not all lipid types or formulations are equally effective, and more research is needed to clarify the benefits of different lipid sources and delivery methods. In summary, there is moderate scientific evidence supporting the use of lipids—especially in topical formulations—for alleviating dermatitis symptoms and improving skin barrier function.
Other ingredients used for Dermatitis
Aloe veraalpha-pinene
beeswax
beta caryophyllene
bisabolol
black currant
black walnut
burdock
Cannabis sativa oil
chamomile
coating
turmeric
forsythia
garlic bulb
ginger
gotu kola
green tea
hemp oil
hyaluronic acid
Lactoperoxidase
lauric acid
Niacinamide (vitamin B3)
oregon grape
phenolic compounds
plantain
pomegranate
purified silver
quercetin
resveratrol
riboflavin (vitamin B2)
rosemary
schizonepeta
scrophularia root
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
vitamin A
vitamin D
vitamin E
Zinc
chickweed
xanthium (cockleburs)
Mugwort
Neem tree
commiphora
siler root
oriental arborvitae
birch
polyphenols
fulvic acid
eucalyptus
Menthol oil
melaleuca alternifolia
geranium
avens
alpha-terpineol
azelaic acid
Ardisia
anamu
Allantoin
Asteraceae
argan nut oil
bee propolis
babchi
Baphicacanthus cusia
Bidens pilosa
bishop\'s weed
Boswellic Acid
Butea monosperma
Barleria
bisabolene
bee products
Bombax
Bassia scoparia
coconut
Centella triterpenes
caryophyllene
Calendula
chlorophyllin
coconut oil
colloid
carvacrol
Curcuminoid
Chinese raisintree
curcumen
Centella asiatica
Centipeda
Curcuma
cannabidiol
Carthamus
copaiba oil
cannabigerol
chrysophanics
Dianthus
Epidermal Growth Factor
Eclipta
emu oil
Euphorbia
ethyl linoleate
flavonoids
fang-feng
fatty acids
Ficus simplicissima
fibroblast growth factor
gallic acid
Gnaphalium
glyceryl monolaurate
Growth factors
Glechoma hederacea
gallotannin
Glycyrrhetinic acid
heal-all
Hydrocolloid
henna
Himalaya berry
hemp
iridoid glycosides
Indian fagonia
jojoba oil
Kokilaksha
Litsea
lichen
Laggera pterodonta
linseed oil
Lantana camara
Leptospermum scoparium
Labdanum
mallow
Melia
Malva sylvestris
mangostin
Mahonia
Milkweed
Marine colloids
marigold
Marking Nut Tree
Macaranga indica
Nigella seed
Oxystelma
Propolis
Phyllanthus
Pentacyclic triterpenoids
Paris polyphylla
Pansit-pansitan
Panthenol
Patrinia
Palmitoylethanolamide (PEA)
Peptides
rue
rosmarinic acid
reed herb
Squalene
Sichuan Lovage
Sicklepod
Sophora
Sesbania
Solanaceae
Shark Liver Oil
Self-Heal
Sweet Annie
Salvia
Sensitive Plant
Southern Tsangshu
Silk protein
Sandalwood
Sulfur
Storax
Terpenoids
Thymoquinone
Terpinen-4-ol
Thymus
Thymol
Tea Tree Oil
Violet
Wrightia tinctoria
Witch Hazel
Zingiberene
Other health conditions supported by Lipids (unspecified)
Body BuildingCancer Treatment (reducing side effects)
Depression
Dermatitis
Eczema
Energy (lack of)
Free Radical Damage
