Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sage (Salvia officinalis) has a long history of use in traditional medicine for a variety of ailments, including mood-related conditions such as depression. In traditional European herbalism and some other folk medicine practices, sage was often used for its reputed calming effects and its ability to lift spirits. These uses were based on empirical observations rather than controlled scientific studies. The herb was commonly included in teas and remedies intended to improve mood, alleviate melancholy, and promote mental clarity.

However, while there is some historical precedent for using sage in relation to mood disorders, robust scientific evidence directly supporting its efficacy in treating depression remains limited. Some preliminary studies have investigated the neuroprotective and cognitive-enhancing effects of sage extracts, noting improvements in mood and cognitive performance in small trials, but these often focus on cognitive decline or anxiety rather than clinical depression. The mechanisms proposed include sage's antioxidant properties, modulation of neurotransmitters, and anti-inflammatory effects, but clinical trials specifically targeting depression are scarce.

In summary, sage’s use in supporting or treating depression is primarily justified by tradition with limited scientific investigation and modest evidence. Its traditional reputation for improving mood persists in herbal lore, but it should not be considered a proven or primary therapeutic option for depression based on current scientific standards.

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Products containing sage

Nature's Sunshine CC-A
Nature's Sunshine CC-A With Yerba Santa Combination Extract
Nature's Sunshine HSN-W
Nature's Sunshine Sage