Evidence supporting the use of: Commiphora
For the health condition: Depression

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Commiphora species, particularly Commiphora mukul (guggul) and Commiphora myrrha (myrrh), have a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine. These resins are primarily used for their anti-inflammatory, analgesic, and lipid-lowering properties. In Ayurvedic texts, guggul is sometimes described as having effects on the nervous system and is considered a "rasayana," or rejuvenative tonic, which may include mood-enhancing properties. Myrrh, similarly, has been used for spiritual and emotional well-being, such as in incense or rituals intended to promote mental clarity and calmness. However, there is very limited direct traditional evidence specifically linking Commiphora species to the treatment or support of clinical depression as understood today. Most claims are extrapolated from its broader use for general vitality, stress relief, or in complex herbal formulas.

From a scientific perspective, there is scant direct evidence to support the use of Commiphora for depression. Some animal studies suggest possible neuroprotective or mild anxiolytic effects of certain Commiphora extracts, but these are preliminary and not directly indicative of antidepressant activity. No well-designed human clinical trials have evaluated Commiphora's efficacy for depression. Thus, its use for depression is justified more by traditional and anecdotal practices than by robust scientific validation, and the evidence supporting this use is weak.

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