Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Phosphate salts are scientifically validated in the management and prevention of dehydration, particularly as part of oral rehydration solutions (ORS). ORS are widely used to treat dehydration caused by diarrhea, vomiting, or other conditions leading to significant fluid loss. The standard composition of ORS, as recommended by the World Health Organization (WHO), includes not only sodium and glucose but also potassium and phosphate salts. Phosphates are essential for maintaining acid-base balance and cellular energy metabolism, and their inclusion in rehydration solutions helps restore electrolyte balance and prevent complications such as metabolic acidosis, which can occur during severe dehydration.

There is robust evidence from clinical trials and decades of practical use supporting the effectiveness of phosphate-containing ORS in reducing morbidity and mortality associated with dehydration, particularly in children in low-resource settings. Phosphate supplementation is especially important when dehydration is accompanied by significant electrolyte losses. The addition of phosphate salts to rehydration solutions is based on both physiological rationale and empirical evidence, as outlined in WHO and UNICEF guidelines.

In summary, the use of phosphate salts in supporting and treating dehydration is grounded in strong scientific evidence and is a standard component of medically approved rehydration therapies.

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