Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ornithine ketoglutarate (OKG) is used to support convalescence—periods of recovery after illness or surgery—primarily based on scientific evidence, although the strength of evidence is moderate. OKG is a salt combining ornithine and alpha-ketoglutarate, both of which are involved in protein metabolism and may help stimulate protein synthesis and reduce protein breakdown. Clinical studies, particularly in elderly or malnourished patients and those recovering from trauma or surgery, have shown that OKG supplementation can improve nitrogen balance, promote muscle protein anabolism, and potentially accelerate recovery. Some studies have reported benefits such as reduced muscle wasting, improved wound healing, and shorter hospital stays in specific patient populations.

However, the quality of available studies varies; many are small, lack rigorous controls, or are dated. Reviews and meta-analyses suggest that while OKG appears promising for enhancing recovery in catabolic states, more robust, large-scale clinical trials are needed to fully establish its efficacy and optimal usage. Current guidelines do not universally endorse OKG for all convalescent patients, but it may be considered in specific cases—such as severe trauma, burns, or elderly patients at risk of malnutrition—where protein catabolism is particularly pronounced.

In summary, the use of ornithine ketoglutarate for supporting convalescence is justified by moderate scientific evidence, with potential benefits in selected patient groups, but it is not yet universally accepted as standard practice.

More about Ornithine ketoglutarate
More about Convalescence

Other ingredients used for Convalescence

Other health conditions supported by Ornithine ketoglutarate

Products containing Ornithine ketoglutarate