Evidence supporting the use of: Sorbitol
For the health condition: Constipation (children)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Sorbitol is a sugar alcohol that has been widely used as an osmotic laxative for the treatment of constipation in both adults and children. Its mechanism of action involves drawing water into the colon, which softens stools and stimulates bowel movements. There is substantial scientific evidence supporting its efficacy and safety in pediatric patients. Several clinical studies and reviews have demonstrated that oral sorbitol solutions are effective in relieving constipation in children, often with a favorable safety profile compared to stimulant laxatives. For example, a review published in Pediatrics notes that sorbitol, found in certain juices (such as prune or pear juice), can be useful in treating mild constipation in infants and young children. Additionally, sorbitol is an ingredient in some commercially available pediatric laxative products.
While sorbitol is generally considered safe, excessive doses may lead to abdominal cramping, diarrhea, or electrolyte imbalances, so dosing should be carefully monitored. The American Academy of Pediatrics recognizes the use of sorbitol-containing juices as a first-line intervention for mild constipation in young children. In summary, the use of sorbitol for pediatric constipation is supported by scientific evidence, clinical trials, and professional guidelines, warranting a high evidence rating.
Other ingredients used for Constipation (children)
2'-Fucosyllactosealoe vera
apple
apricot
bacillus coagulans
bamboo
basil
beet
myrobalan
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bio ecolian (proprietary)
blackberry
blueberry
bасора
carrot
chamomile
chicory
cinnamon
citrus sinensis (proprietary)
coconut milk
Coptis chinensis
cowage seed
cucumber
turmeric
d-sorbitol
fennel
fiber blend (proprietary)
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
grape
green banana
guar gum
cellulose
Indian tinospora
inulin
isomalto-oligosaccharide
jujube
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus gasseri
lactobacillus reuteri
lemon
mannitol
moringa
nettle
orange
pear
phellodendron amurense
pineapple
plum fruit
pomegranate
potato starch
prebiotic blend (proprietary)
prune
psyllium
pumpkin
raspberry
rhizome
slippery elm bark
sorbitol
spinach
streptococcus thermophilus
tomato
triphala
almond fruit
vegetable and fruit blend (proprietary)
seaweed
watermelon
squawvine
cascara sagrada
tangerine
atractylodes
papaya
mugwort
Indian bael
nut grass
alpinia galangal
anise
punarnava
blackboard tree
root tuber
dioscorea
dodder
sweet flag
polyphenols
senna
peach
indigo leaves
soursop
Agar
Anthraquinone
Ardisia
Amomum
Alexandrian senna
Aloin
Appleblossom Cassia
Asam gelugor
Asteracea
Arabinoxylan
Allium tuberosum
Amor seco
Atractylone
Black Seed
Bifidobacterium
Bifidobacterium adolescentis
Bidens pilosa
Broussonetia
Bishop's Weed
Belleric myrobalan
Bran
Bitter Grass
Bael
Butternut
black salt
Bifidobacterium animalis
Bee products
Bombax
Borassus Palm
Bacteria
Bifidobacteria
Bacillus
Bassia scoparia
Bottle gourd
Borneol
Coconut
Curry leaf
Cascaroside
Cactus
Cynomorium
Citrus
Cantaloupe
Cyclanthera pedata
Chenopodium
Curcuma
Cabbage
Chirata
Clostridium butyricum
Castor Oil
Celosia
Currant
Chondrus
Dianthrone
Date
Eclipta
Fig
Galangal
Phosphate Salt
Rhubarb
Wheat
Zucchini
Other health conditions supported by sorbitol
Constipation (adults)Constipation (children)
Digestion (poor)