Evidence supporting the use of: Ribose
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Ribose is a naturally occurring sugar that plays a key role in the synthesis of adenosine triphosphate (ATP), the primary energy carrier in cells. Its use in supporting or treating Congestive Heart Failure (CHF) is based on the hypothesis that supplementing ribose may help replenish ATP stores in energy-depleted heart muscle, thereby improving cardiac function. Several small clinical studies and pilot trials have examined this possibility. For example, some research suggests that ribose supplementation can improve diastolic function and exercise tolerance in patients with CHF or ischemic heart disease. However, the sample sizes in these studies are often small, methodologies variable, and many are not double-blinded or placebo-controlled.
Reviews of the evidence, such as those from systematic reviews and the American Heart Association, generally conclude that while ribose shows theoretical promise, the current clinical evidence is limited and not robust enough to support widespread clinical use in CHF. There is no large, high-quality, randomized controlled trial to definitively confirm benefit. As a result, the evidence supporting ribose for CHF is rated low to moderate (2/5), and its use remains experimental. Patients considering ribose should consult with their healthcare provider, as it is not standard therapy for CHF.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
arjun tree
astragalus
black garlic
coenzyme Q10 (CoQ10)
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
garlic bulb
ginseng
hawthorn
l-arginine
l-carnitine
l-citrulline
l-taurine
marine lipid
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
ophiopogon root
potassium
resveratrol
thiamin (vitamin B1)
ubiquinol
vitamin D
zinc
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Arjuna
Allicin
Arginine orotate
Astragaloside
Arjunic Acid
Black Seed
Chinese Silkvine
Catecholamine
Cowherb
Docosahexaenoic Acid
Danshen
Digitalis
Eicosapentaenoic Acid
Foxglove
Fatty acids
Flavanols
Glycoside
Theophylline
Other health conditions supported by Ribose
Athletic and Exercise AidsCardiovascular Disease
Circulation (poor)
Congestive Heart Failure
Energy (lack of)
Fatigue
Fibromyalgia Syndrome
Heart (weakness)