Evidence supporting the use of: Arjunic Acid
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Arjunic Acid is a triterpenoid compound isolated from the bark of Terminalia arjuna, a tree long used in Ayurvedic medicine for cardiovascular health. The traditional use of Terminalia arjuna bark for heart conditions, including congestive heart failure (CHF), is well documented in historical Ayurvedic texts. In terms of scientific validation, some preclinical and limited clinical studies have investigated the effects of Arjunic Acid and Terminalia arjuna extracts on heart function.
Animal studies suggest that Arjunic Acid possesses antioxidant, anti-inflammatory, and cardioprotective properties, potentially beneficial in CHF. These effects are thought to involve improved myocardial contractility, reduced oxidative stress, and modulation of lipid levels. Some small-scale human studies and clinical trials using Terminalia arjuna bark extract (which contains Arjunic Acid among other compounds) have shown improvements in symptoms and cardiac function in CHF patients. However, these studies are limited by small sample sizes, short durations, lack of standardization of extracts, and a focus on the whole bark rather than isolated Arjunic Acid.
Overall, while there is promising preliminary evidence and a strong tradition of use, robust clinical trials specifically targeting isolated Arjunic Acid in CHF are lacking. Thus, scientific support exists but is currently weak to moderate and should be considered preliminary.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
arjun tree
astragalus
black garlic
coenzyme Q10 (CoQ10)
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
garlic bulb
ginseng
hawthorn
l-arginine
l-carnitine
l-citrulline
l-taurine
marine lipid
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
ophiopogon root
potassium
resveratrol
thiamin (vitamin B1)
ubiquinol
vitamin D
zinc
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Arjuna
Allicin
Arginine orotate
Astragaloside
Arjunic Acid
Black Seed
Chinese Silkvine
Catecholamine
Cowherb
Docosahexaenoic Acid
Danshen
Digitalis
Eicosapentaenoic Acid
Foxglove
Fatty acids
Flavanols
Glycoside
Theophylline