Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Gelcap is a term that refers to a gelatin capsule, which is a dosage form rather than a specific medication. However, when referring to over-the-counter (OTC) "Gelcap" products used for colds with fever, these often contain active ingredients such as acetaminophen (paracetamol), ibuprofen, or a combination of analgesics and decongestants. The scientific justification for their use is well established. Acetaminophen and ibuprofen are both antipyretics (fever reducers) and analgesics (pain relievers), and numerous randomized controlled trials and systematic reviews have shown their efficacy in reducing fever and alleviating symptoms such as sore throat, headache, and muscle aches associated with the common cold. While these medications do not treat the underlying viral infection, they provide symptomatic relief, which is a key component of cold management. Guidelines from organizations such as the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) recommend the use of these agents for symptomatic relief in viral respiratory infections, including colds with fever. Therefore, the use of gelcap formulations containing these medications is supported by robust scientific evidence for the management of cold symptoms with fever.

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