Evidence supporting the use of: Pomegranate
For the body system: Circulatory System
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Pomegranate (Punica granatum) has been traditionally valued in various cultures for its health benefits, but in recent years, there is growing scientific evidence supporting its positive effects on the circulatory system. Several clinical and preclinical studies have demonstrated that pomegranate juice and extracts may help improve cardiovascular health by reducing blood pressure, improving lipid profiles, and reducing oxidative stress and inflammation.
One of the most cited benefits is its high content of polyphenols, particularly punicalagins and anthocyanins, which have potent antioxidant properties. Randomized controlled trials have shown that regular consumption of pomegranate juice can lead to significant reductions in systolic and diastolic blood pressure in patients with hypertension. Additionally, studies indicate that pomegranate extract may reduce arterial plaque buildup and improve endothelial function, both of which are critical factors in maintaining healthy circulation.
Meta-analyses and reviews (e.g., Sahebkar et al., Phytotherapy Research, 2017) have concluded that pomegranate supplementation can improve several cardiovascular risk markers. However, some studies show modest or variable results, and more large-scale, long-term trials are needed for definitive conclusions. Overall, the current body of scientific evidence supports the use of pomegranate for circulatory system support, justifying its inclusion in supplements targeting cardiovascular health.
Other ingredients that support Circulatory System
ajoenealfalfa
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
astragalus
barley
basil
beet
berberine
bergamot
Beta-Glucan
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
bovine liver
broccoli
brussel sprouts
burdock
butcher's broom
caffeine
calamari oil
calcium
campesterol
canola oil
capsaicinoids
cassia bark
catechins
caterpillar mushroom
cauliflower
celery
cherry
chia seed
Chinese salvia root
chlorella
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
coleus forskohlii
collard
copper
cottonseed oil
cordyceps
turmeric
curcumin
cuspidatum root
d-alpha tocopherol
dandelion
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dog rose
dong quai root
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
fennel
fenugreek
fiber blend (proprietary)
fisetin
fish oil
fish protein
flavonols
flaxseed
forskohlii root
fruit and vegetable blend (proprietary)
gamma linolenic acid (GLA)
gamma tocopherol
garlic bulb
ginger
ginkgo biloba
ginseng
gokhru
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
greens blend (proprietary)
guggul
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
iron
knotweed
Japanese sophora
kale
krill oil
kudzu
l-arginine
l-carnitine
l-citrulline
l-taurine
lignans
linoleic acid (LA)
luteolin
lycopene
mackerel
magnesium
mango
mangosteen
maqui berry
marine lipid
matcha
moringa
motherwort
mustard seed
naringin
nattokinase
nattozimes
nettle
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
okra
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-9 fatty acids
orange
oyster mushroom
palmitoleic acid
pantethine
parsley
phenolic acids
phytosterols
pine bark
plant sterols
policosanol
pomegranate
pomelo
potassium
quercetin
quinoa
raspberry
red yeast rice
rehmannia glutinosa
reishi mushroom
resveratrol
rhizome
rose hips
rosemary
rutin
safflower oil
sardines
scrophularia root
secoisolariciresinol diglucoside
selenium
black ginger
sitostanol
soybean
spinach
spirulina
sterols
strawberry
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
triphala
almond fruit
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vinpocetine
vitamin B
vitamin C
vitamin D
vitamin D3
vitamin E
vitamin K
seaweed
water
watercress
watermelon
wheat grass
mulberry
β-nicotinamide mononucleotide (NMN)
sarsaparilla
red clover
suma
jiaogulan
tangerine
gastrodia
lobelia
capsicum
hedychium spicatum
inula racemosa
punarnava
commiphora
rubia cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
yarrow
prickly ash
morus
lemongrass
sodium salt
ferulic acid
chrysanthemum
eucommia
ganoderma
zanthoxylum
electrolytes blend (proprietary)
terpene lactones
polyphenols
trace minerals
purslane
barrenwort
camphor oil
shepherd's purse
yerba mate
wheat germ
noni
wood betony
nopal
amaranth
herbal blend (proprietary)
Sichuan pepper
algae
yohimbe
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
cayenne pepper
cayenne pepper
ashitaba
arnica
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Arjuna
Arginine Alpha Ketoglutarate
Animal Tissue
Arginine Creatine
Arginine nitrate
Asiaticoside
Angelica
Aronia melanocarpa
Allicin
Arginine malate
Arginine aspartate
Achyranthes
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Avocado
Adrenergic amines
Alpha-Lipoic Acid
Astragaloside
Adrenaline
Aescin
anthocyanidins
Ampelopsin
Asteracea
Allyl Sulfide
Alpha phytosterol
Acetylsalicylic acid
Algal protein
Arjunic Acid
Alliin
anthocyanosides
Ashoka
Allium tuberosum
Apocynin
Arginine silicate
Arjunolic acid
Animal protein
Bee Propolis
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Brutieridin
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Brassica
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Ba Ji Tian
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banana
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Bignay
Boerhavia diffusa
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bugleweed
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Camellia sinensis
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Chinese Mountain Ant
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chlorogenic acid
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cypress
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cola nut
Casearia sylvestris
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Docosahexaenoic Acid
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Dihydrocapsaicin
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Delphinidin
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Escin
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Fruit
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Flavonoids
Fo-Ti
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Fish
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Flavanones
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False Flax
Ginsenosides
Guava
Garlic
Gallate
glucose
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Guaranine
Ginkgoheteroside
Guggulsterones
Glucoraphanin
Mustard
Mistletoe
Periwinkle
Pistachio
Rose
Snakeroot (unspecified)
Shellfish
salt
Soy Protein
Sumac
Vervain
walnut
yohimbine
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