Evidence supporting the use of: Black Seed Oil
For the health condition: Chronic Obstructive Pulmonary Disorder
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Black seed oil, derived from Nigella sativa, has a long history of use in traditional medicine for various ailments, including respiratory disorders. Scientific interest has grown in recent years regarding its potential benefits for Chronic Obstructive Pulmonary Disease (COPD). Preclinical studies suggest that thymoquinone, the main bioactive constituent in black seed oil, exhibits anti-inflammatory, antioxidant, and bronchodilatory properties. These effects are theoretically relevant to COPD, a condition marked by chronic inflammation and oxidative stress in the airways.
A handful of small-scale, randomized controlled trials and observational studies have investigated black seed oil in patients with asthma and, less frequently, COPD. Some evidence suggests improvements in certain lung function parameters and reductions in inflammatory markers. For example, a small clinical trial published in 2017 found that Nigella sativa supplementation led to modest improvements in pulmonary function tests in patients with partially controlled asthma. Data specific to COPD, however, remain limited; most studies involve animal models or focus on asthma rather than COPD. No large, high-quality clinical trials have definitively confirmed its efficacy or safety in COPD patients.
In summary, while there is scientific plausibility and preliminary evidence supporting black seed oil’s role in respiratory health, the direct evidence for its use in COPD is weak and rated as low (2/5). Further research, particularly well-designed clinical trials in COPD populations, is necessary before black seed oil can be recommended as a standard adjunct treatment.
More about Black Seed Oil
More about Chronic Obstructive Pulmonary Disorder
Other ingredients used for Chronic Obstructive Pulmonary Disorder
Acetyl L-carnitineamino acids
anthocyanins
ashwagandha
astragalus
beta caryophyllene
black cumin
cat's claw
caterpillar mushroom
Chinese salvia root
cordyceps
turmeric
curcumin
fish oil
garlic bulb
ginger
green tea
Indian tinospora
licorice root
luteolin
Marine lipid
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
prebiotic blend (proprietary)
quercetin
reishi mushroom
resveratrol
rhizome
specialized pro-resolving mediators (SPMs)
spirulina
Triphala
vitamin C
vitamin D
Mullein
Tinospora cordifolia
lingzhi
buckthorn
dodder
ganoderma
polyphenols
herbal blend (proprietary)
AMP-activated protein kinase (AMPK)
Agarikon Mushroom
Auricularia
andrographolide
Adrenergic amines
astragaloside
apocynin
atractylone
Baikal Skullcap
baicalein
Boswellia
Baccharoides anthelmintica
Bombax
bacteria
baicalin
Bassia scoparia
Boerhavia diffusa
Codonopsis
capillary artemisia
cowherb
dismutase
danshen
eicosapentaenoic acid
gamma-glutamylcysteine
Glutathione
Hygrophila
Hedyotis
Indian kinotree
Ophiopogon
Oxystelma
Phyllanthus
Pyrrosia
paeoniflorin
Sulforaphane
Thymoquinone
Triterpenes
Theophylline
Tremella
Withanolides
Wulinshen
Other health conditions supported by Black Seed Oil
AcneAllergies (respiratory)
Anemia
Antibiotics (alternatives to)
Anxiety
Arthritis
Asthma
Backache
Boils
Bronchitis
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Constipation (adults)
Cuts
Depression
Dermatitis
Diabetes
Diarrhea
Digestion (poor)
Eczema
Emphysema
Fatigue
Fever
Fungal Infections
Gastritis
Gingivitis
Gout
Hair (loss or thinning)
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hepatitis
Herpes
Hypertension
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Insomnia
Jaundice (adults)
Liver Detoxification
Lupus
Malaria
Migraine