Synopsis

Source of validity: Traditional
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Helicteres isora, commonly known as the Indian screw tree, has a history of use in traditional medicine systems such as Ayurveda and folk medicine in India. One of its attributed uses is in the treatment of gastrointestinal disorders, including diarrhea and dysentery, which are symptomatically similar to cholera. The roots and fruits of Helicteres isora have been traditionally used as remedies for various digestive ailments, and some ethnobotanical surveys and Ayurvedic texts mention its utility for symptoms that may overlap with cholera, such as severe diarrhea. However, the evidence supporting this use is largely anecdotal and based on traditional knowledge rather than rigorous scientific validation.

There are very limited modern scientific studies specifically investigating the efficacy of Helicteres isora against Vibrio cholerae, the causative agent of cholera. Some laboratory studies have reported antimicrobial and antidiarrheal properties of plant extracts, but these findings are preliminary and not directly linked to clinical cholera infection. Therefore, while the use of Helicteres isora for cholera has a basis in traditional practice, it lacks robust scientific evidence and should not be relied upon as a sole treatment for cholera, which is a potentially life-threatening disease requiring prompt medical attention and rehydration therapy.

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