Evidence supporting the use of: Terpenoids
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Terpenoids, also known as isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. There is a moderate degree of scientific evidence supporting the use of certain terpenoids for supporting capillary health and function. Many plant-based terpenoids, such as those found in ginkgo biloba (ginkgolides), horse chestnut (aescin), and gotu kola (asiaticoside), have been studied for their vascular effects, including capillary protection and improvement of microcirculation. Research has shown that some terpenoids possess antioxidant, anti-inflammatory, and vasoprotective properties. For example, aescin from horse chestnut has been shown in clinical studies to reduce capillary permeability and improve symptoms of chronic venous insufficiency, likely by strengthening capillary walls and reducing fluid leakage. Ginkgo biloba extract, rich in terpenoids, has been found to improve peripheral circulation and decrease capillary fragility. However, it is important to note that while these effects have been observed with specific terpenoid-containing extracts, the evidence is not universal for all terpenoids, and the quality of studies varies. Overall, terpenoids have a moderate level of scientific support for their role in supporting capillary integrity and function, primarily based on studies of specific compounds within this large class.

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