Evidence supporting the use of: Polyphenols (unspecified)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Polyphenols are a diverse group of naturally occurring compounds found in plants, notably in fruits, vegetables, tea, wine, and cocoa. Their use to support capillary health is primarily justified by scientific evidence. Numerous studies have investigated the effects of polyphenols—particularly flavonoids, a major subgroup—on vascular and capillary function.

Research has shown that polyphenols have antioxidant, anti-inflammatory, and vasoprotective properties. These compounds can improve endothelial function, reduce oxidative stress, and increase capillary resistance, which may help protect and strengthen capillary walls. For instance, flavonoids such as diosmin, rutin, and hesperidin have been used therapeutically to treat chronic venous insufficiency and capillary fragility, with clinical trials supporting their efficacy in reducing symptoms like edema, leg heaviness, and microbleeding.

Polyphenols are believed to enhance capillary health by modulating nitric oxide production, thus improving vasodilation and microcirculation. Additionally, their antioxidant activity helps prevent oxidative damage to the vascular endothelium and connective tissue of capillaries.

While much of the evidence comes from studies using specific polyphenols rather than broad, unspecified mixtures, the overall scientific consensus supports the beneficial role of polyphenols in maintaining capillary integrity and function. However, the precise effects can vary depending on the specific polyphenol and dosage used.

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