Evidence supporting the use of: Leucoanthocyanins
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Leucoanthocyanins, more commonly referred to as proanthocyanidins or condensed tannins, are polyphenolic compounds found in a variety of plants, including grapes, apples, pine bark, and certain berries. Their use to support the capillary system is primarily justified by scientific research, especially in the context of vascular health. A significant body of evidence has shown that proanthocyanidins can strengthen capillary walls, reduce capillary permeability and fragility, and improve microcirculation. These effects are attributed to their antioxidant properties and their ability to stabilize collagen and elastin in blood vessel walls. For example, studies on extracts such as grape seed extract (rich in oligomeric proanthocyanidins) and French maritime pine bark (Pycnogenol) have demonstrated improved capillary resistance and reduced edema in both animal and human models (Blauz & Kuntz, 2004; Fitzpatrick et al., 1998). Clinical trials—while variable in quality—have reported benefit in conditions characterized by capillary fragility, such as chronic venous insufficiency, diabetic retinopathy, and hemorrhoids. However, while the mechanistic and preliminary clinical evidence is supportive, large-scale, rigorous, long-term human trials are still limited. Therefore, the evidence supports the use of leucoanthocyanins for capillary health, but further research is needed for definitive conclusions and widespread medical endorsement.

More about Leucoanthocyanins
More about Capillaries

Other body systems supported by Leucoanthocyanins

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gums
Heart
Skin
Veins

Products containing Leucoanthocyanins

We currently have no products on Caring Sunshine that contain this ingredient.