Evidence supporting the use of: Leucoanthocyanidins
For the body system: Capillaries
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Leucoanthocyanidins, also known as proanthocyanidins or condensed tannins, are polyphenolic compounds found in various plants, such as grapes, apples, and cocoa. Their use to support capillary health primarily stems from traditional herbal medicine practices, particularly in European phytotherapy, where plant extracts rich in these compounds (such as grape seed extract and hawthorn) have been used to promote vascular strength and reduce capillary fragility. Leucoanthocyanidins are believed to help stabilize collagen and elastin in blood vessel walls, theoretically reducing permeability and increasing resistance to damage.
There is some scientific interest in the effects of proanthocyanidins on vascular health, but direct, robust clinical evidence specifically linking leucoanthocyanidins to improved capillary function is limited. Most studies focus on broader plant extracts (e.g., grape seed or pine bark), which contain a mix of polyphenols, rather than isolated leucoanthocyanidins. Some small studies and in vitro research suggest that these compounds may reduce capillary permeability and have antioxidant effects, but the quality and quantity of clinical trials are insufficient for strong scientific validation.
Overall, the use of leucoanthocyanidins for capillary support is primarily justified by traditional use and plausible mechanisms rather than extensive scientific confirmation.
Other ingredients that support Capillaries
Aescinalpha-glycosyl isoquercitrin
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
Aronia melanocarpa
ashitaba
asiaticoside
astragalin
astragalus
baicalein
Baikal Skullcap
benfotiamine
berry
bilberry
bioflavonoids
black currant
blueberry
butcher's broom
capers
capsicum
cayenne pepper
Centella asiatica
Centella triterpenes
Chinese salvia root
chokeberry
Citrus
citrus bioflavonoids
coca
Collinsonia
coumarin
cranesbill
cyanidin
cypress
danshen
delphinidin
dextran
diosmetin
Diosmin
eicosapentaenoic acid
epicatechin
Erigeron
escin
Fagopyrum
fatty acids
fish oil
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
fruit
garlic bulb
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
gotu kola
grape
Gypenoside
hawthorn
herbal blend (proprietary)
hesperidin
horse chestnut
Hyperoside
Immortelle
Japanese sophora
L-arginine
leucoanthocyanidins
Ligusticum
Ligustrazin
linden
lingzhi
Mineral ascorbate
Nattokinase
Oligomeric proanthocyanidins
onion
orange
pagoda tree
Pentacyclic triterpenoids
Periwinkle
phenolic compounds
Phenylpropanoids
Phosphate ascorbate
pine bark
Polydatin
polymethoxylated flavones
polyphenols
prickly ash
proanthocyanidins
procyanidin
procyanidol
punicalagins
purslane
Pycnogenol
quercetin
rue
Ruscogenins
Ruscus
rutin
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
shepherd's purse
Stone Root
Sweet Clover
Taxifolin
terpene lactones
Terpenoids
Troxerutin
Vincamine
vitamin B
vitamin C
vitamin E
vitamin K
Vitexin
Witch Hazel
Xantinol Nicotinate
Yarrow
Yarrow
Yumberry
