Evidence supporting the use of: Gotu kola
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Gotu kola (Centella asiatica) has a long history of traditional use, but its application for supporting capillary health and microcirculation is also supported by scientific evidence. Several studies have investigated the effects of gotu kola extracts, particularly those standardized to triterpenoids, on venous insufficiency and capillary permeability. Clinical trials have demonstrated that gotu kola can reduce edema, improve microcirculatory parameters, and decrease capillary filtration rates in patients with chronic venous insufficiency. The proposed mechanisms include strengthening of capillary walls, modulation of collagen synthesis, and reduction of oxidative stress in vascular tissues. A systematic review (Cesarone et al., 2001) and subsequent clinical research have found that gotu kola can improve subjective symptoms (such as heaviness and swelling) and objective measurements (such as capillary filtration rate) compared to placebo. However, while the evidence is promising and consistent across several small to moderate-sized studies, larger and more rigorous clinical trials are needed to confirm its efficacy and optimal dosing. Thus, the use of gotu kola for supporting the capillaries is justified by both traditional use and emerging scientific validation, meriting a moderate evidence rating.

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