Evidence supporting the use of: Capsaicin
For the health condition: Burning Feet or Hands

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Capsaicin, the active compound in chili peppers, is scientifically validated for use in treating burning sensations in the feet or hands, most commonly due to neuropathic pain conditions such as diabetic neuropathy or postherpetic neuralgia. Capsaicin works by depleting substance P, a neuropeptide involved in transmitting pain signals to the brain. Topical capsaicin creams or patches have been shown in multiple randomized controlled trials to reduce pain intensity and burning sensations in patients with neuropathic pain. For example, a 2008 Cochrane review concluded that topical capsaicin is more effective than placebo for neuropathic pain, though it may cause local irritation or burning at the application site initially.

High-concentration capsaicin patches (8%) are approved by regulatory agencies such as the FDA and EMA for neuropathic pain. These patches are applied under medical supervision and can provide prolonged relief for up to several weeks. Most evidence pertains to chronic neuropathic conditions rather than acute injuries or other causes of burning hands/feet. While capsaicin's efficacy is well-established for neuropathic pain, it is not a cure and should be used as part of a broader pain management plan. In summary, the use of capsaicin for burning feet or hands is supported by robust scientific evidence, particularly in the context of neuropathic pain syndromes.

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Products containing Capsaicin

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