Evidence supporting the use of: Khella
For the body system: Bronchials

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Khella (Ammi visnaga) has been traditionally used in various cultures, particularly in the Middle East and North Africa, to support the bronchial system. The plant's dried fruits have been employed in folk medicine for respiratory issues such as asthma, bronchitis, and cough. Historically, the primary active constituents, khellin and visnagin, were noted for their bronchodilatory effects, which may help to relax bronchial smooth muscle and ease breathing.

Scientific studies on Khella are limited, but some early pharmacological research (primarily from the mid-20th century) suggested that khellin, a furanochromone compound, can act as a mild bronchodilator and antispasmodic. Khellin was even a precursor in the development of cromolyn sodium, a mast cell stabilizer used in asthma management. However, the direct clinical use of Khella or khellin for bronchial support has not been widely adopted in modern medicine due to limited efficacy, potential toxicity at higher doses, and the availability of safer, more effective drugs.

In summary, while there is a notable tradition of using Khella to aid bronchial health and some pharmacological rationale, robust clinical evidence is lacking. Its current use is thus justified primarily by traditional practices rather than strong scientific validation.

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