Evidence supporting the use of: Flax lignans
For the body system: Breasts

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flax lignans, particularly secoisolariciresinol diglucoside (SDG), have been studied for their potential effects on breast health due to their phytoestrogenic properties. Phytoestrogens are plant-derived compounds that can weakly bind to estrogen receptors and may exert both estrogenic and anti-estrogenic effects. Several observational studies and small clinical trials have explored the possible protective role of flaxseed or its lignans against hormone-dependent cancers, including breast cancer. Some studies suggest that flaxseed consumption may modestly reduce breast cancer risk or influence biomarkers associated with breast health, such as estrogen metabolism and cell proliferation in breast tissue. Meta-analyses indicate a possible association between higher lignan intake and reduced breast cancer risk, especially in postmenopausal women, but evidence is not conclusive, and more large-scale, well-controlled trials are needed. The mechanism is thought to involve modulation of estrogen activity and metabolism, as well as anti-inflammatory and antioxidant effects. While traditional use specifically for breast health is not well documented, current use is largely based on these scientific findings. Therefore, the use of flax lignans for supporting the breast body system is justified by emerging scientific evidence, albeit with moderate strength and ongoing debate in the scientific community.

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