Evidence supporting the use of: Creatine monohydrate
For the health condition: Body Building

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Creatine monohydrate is one of the most extensively researched and scientifically validated supplements for supporting bodybuilding and athletic performance. Numerous peer-reviewed studies have demonstrated that creatine supplementation increases intramuscular phosphocreatine stores, which can enhance the regeneration of adenosine triphosphate (ATP) during short bursts of high-intensity activities such as weightlifting and sprinting. This physiological effect translates into improved strength, increased lean muscle mass, and enhanced performance during repeated bouts of intense exercise.

The International Society of Sports Nutrition (ISSN) and other scientific bodies recognize creatine monohydrate as both effective and safe for most individuals when used appropriately. Meta-analyses have shown that creatine supplementation provides significant improvements in maximal strength, muscular endurance, and hypertrophy, especially when combined with resistance training. The safety profile of creatine is well-established, with no consistent evidence of adverse effects in healthy individuals when used at recommended doses (typically 3-5 grams per day after an initial loading phase, if any).

While creatine is naturally found in foods such as red meat and fish, supplementation allows individuals to achieve higher muscular concentrations, maximizing its ergogenic potential. The robust body of scientific evidence supporting creatine monohydrate’s efficacy and safety makes it a mainstay in the bodybuilding community, not just by tradition but by clear, reproducible scientific validation.

More about creatine monohydrate
More about Body Building

Other ingredients used for Body Building

7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
Coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
L-cysteine
L-glutamine
L-glycine
L-leucine
L-methionine
L-ornithine
L-valine
magnesium
maltodextrin
Milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
Almond fruit
vitamin D
Whey protein
Zinc
wheat germ
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
4-DHEA
arginine alpha ketoglutarate
arachidonic acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
anti-aromatase
animal protein
Beef Protein
beef
Beef liver
bovine protein
beta-lactoglobulin
ba ji tian
banana
chia seed
casein
cardarine
Citrus
capsaicin
capsiate
D-Aspartic Acid
dihydrocapsiate
deer velvet
D-Ribose
dextrose
eurycomanone
egg
Eurycoma Longifolia
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
Egg protein
fungus
Fadogia agrestis
forskolin
glucose
hydroxymethylbutyrate
HMB hydroxymethylbutyrate
Isoleucine
ketosterones
leucine alpha-ketoglutarate
lactalbumin
lactoglobulin
lipids
Marine protein
Milk Protein
Phytoecdysteroid
Protodioscin
Phosphatidic Acid
Palatinose
propionate ester
Peptides
Rhaponticum
Synephrine
Safed musli
Ursolic Acid
Yohimbine
Zucchini

Products containing creatine monohydrate