Evidence supporting the use of: Goldthread (unspecified)
For the health condition: Blood Poisoning

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldthread (Coptis spp.) is a traditional herbal remedy used in various systems of traditional medicine, particularly in Chinese and Native American medicine. Historically, goldthread has been employed for its antimicrobial, anti-inflammatory, and bitter properties. In the context of "blood poisoning" (a historical term often referring to sepsis or systemic infection), goldthread was used in traditional Chinese medicine (TCM) formulations to "clear heat" and "detoxify the blood." The active compound, berberine, is known for its antibacterial effects, which may have contributed to its historical use against infections. However, while in vitro studies have demonstrated berberine's antimicrobial activity, there is limited to no clinical evidence supporting the effectiveness of goldthread or its constituents in treating sepsis or serious systemic infections in humans. Its historical use reflects the empirical approaches of traditional medicine rather than evidence-based practice. Modern clinical guidelines for sepsis or blood poisoning do not recognize goldthread as a treatment. Therefore, its use for "blood poisoning" is justified primarily by tradition, with minimal scientific validation and low evidence supporting its efficacy for this condition.

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