Chanca Piedra (Phyllanthus niruri) has a long history of use in traditional medicine, particularly in South America, India, and China, for various urinary tract conditions, including the presence of blood in urine (hematuria). In folk medicine, it is most renowned for its use as a remedy for kidney stones and urinary tract infections – conditions that can sometimes cause hematuria. Traditional practitioners believe that Chanca Piedra helps "break stones" and soothe the urinary tract, potentially reducing irritation and bleeding.

However, direct scientific evidence supporting its use specifically for blood in urine is limited. Some laboratory and animal studies suggest that extracts of Phyllanthus niruri may reduce kidney stone formation, decrease inflammation, and protect the urinary tract lining. These effects could, in theory, help alleviate hematuria when it is caused by stones or infections. A few small clinical trials indicate Chanca Piedra may promote the passage of stones, which could indirectly reduce bleeding, but they do not focus on hematuria as a primary outcome.

In summary, the use of Chanca Piedra for blood in urine is primarily based on traditional practices, with only indirect or preliminary scientific support for its efficacy in this specific context. More rigorous clinical studies would be needed to validate its direct effectiveness for treating or preventing hematuria.